Apr. 30, 2024 Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts. A protein's structure is critical to its function. Malformed proteins not only fail to carry out their tasks, they can accumulate and eventually gum up the inner workings of cells. As a result, misfolded proteins cause a variety of degenerative diseases, from Alzheimer's and ...
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Apr. 30, 2024 A research team embarked on a quest to understand the diversity and cellular mechanisms of human Th2 cells. By conducting gene expression analyses of inflamed tissues, they pinpointed a subset of Th2 cells called Th2-MPP cells. Their findings suggested that these cells might serve as precursors to several crucial Th2 cell populations responsible for disease symptoms. These discoveries lay the ...
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Apr. 30, 2024 Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in ...
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Apr. 30, 2024 Loneliness in adulthood follows a U-shaped pattern: it's higher in younger and older adulthood, and lowest during middle adulthood, reports a new study that examined nine longitudinal studies from around the world. The study also identified several risk factors for heightened loneliness across the whole lifespan, including social isolation, education and physical ...
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Apr. 30, 2024 Researchers have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective ...
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Apr. 22, 2024 Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's ...
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Apr. 22, 2024 Drug effects have dominated the national conversation about psychedelics for medical treatment, but a new study suggests that when it comes to reducing depression with psychedelic-assisted therapy, what matters most is a strong relationship between the therapist and study ...
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Apr. 23, 2024 Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study. The phenomenon may provide an opportunity to learn more about the neurodegeneration process, and the technique used to make this discovery is readily applicable to other ...
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Apr. 30, 2024 Electric bicycle rebates have exploded in popularity in North America as transportation planners try to get people out of their cars and into healthier, more climate-friendly alternatives. However, questions remain: Are new cycling habits sustainable? Who benefits most from these incentives? And are they worth the cost? Researchers now have some ...
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Apr. 29, 2024 A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say ...
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Apr. 29, 2024 A new study shows that school entry requirements are linked to an increase in human papillomavirus (HPV) ...
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Apr. 29, 2024 A bright yellow pigment favored a century ago by Impressionists such as Matisse and Van Gogh is losing its luster. Researchers have developed a laser imaging technique that can detect the first tiny signs of the pigment's breakdown before they're visible to the eye. The work could help art conservators take earlier steps to make the color ...
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